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Ata
(Acinetobacter trimeric autotransporter) |
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Important for adhesion to host extracellular matrices (collagen and laminin) and basal membrane components. ... |
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CpaA
(Coagulation targeting metallo-endopeptidase of A. baumannii) |
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CpaA is the best characterized and most abundant effector secreted by several medically relevant Acinetobacter strains. CpaA stability and secretion depend on the membrane-bound chaperone CpaB, which is encoded adjacent to CpaA. ... |
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| BmaA |
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Monomeric autotransporter that shares significant sequence similarities with BmaC. The bmaA and bmaC loci from Brucella melitensis are pseudogenes. ... |
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| BmaB/OmaA |
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Monomeric autotransporter that shares significant sequence similarities with BmaC. Contributes to adhesion of B. suis to host cells as well as to extracellular matrix components such as fibronectin. ... |
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| BmaC |
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A large 340 kDa-protein with a long N-terminal cleavable 72 amino acid signal peptide and several adhesion-related motifs within the passenger domain, an extended pectin lyase virulence factor domain, and several passenger-associated-transport-repeats (PATR). ... |
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| BtaE |
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Both the BmaC and BtaE adhesins are consistently associated with the new cell pole, suggesting that, in Brucella, the new pole is functionally differentiated for adhesion. ... |
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| BtaF |
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Trimeric autotransporter involved in the adhesion to various ECM components (i.e. fibronectin, hyaluronic acid, fetuin, type I collagen) and to human cervical and alveolar epithelial cells. ... |
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BtpA/Btp1/TcpB
(TIR domain-containing protein) |
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Translocated by Brucella into host cells. May be substrates of the VirB T4SS. Contains Toll-interleukin-1 receptor (TIR) domain. ... |
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| BtpB |
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Translocated into host cells. May be the substrates for the VirB T4SS. TIR domain-containing protein BtpB also interfere with Toll like receptor signalling to temper the host inflammatory response. Also modulates microtubule dynamics. ... |
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Pmps
(Polymorphic membrane proteins) |
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The largest chlamydial protein family, with 9 members (subdivided into six subtypes) in C. trachomatis and 21 in C. pneumoniae, and are characterized by the presence of multiple copies of GGA(I,L,V) and FxxN motifs. Very heterogeneous not only in their number, but also in sequence. ... |
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