Homepage Search in the database Current status Feedback Link to resources Contact us

INTERFACE
Bacteria
Acinetobacter
Aeromonas
Anaplasma
Bacillus
Bartonella
Bordetella
Brucella
Burkholderia
Campylobacter
Chlamydia
Clostridium
Corynebacterium
Coxiella
Enterococcus
Escherichia
Francisella
Haemophilus
Helicobacter
Klebsiella
Legionella
Listeria
Mycobacterium
Mycoplasma
Neisseria
Pseudomonas
Rickettsia
Salmonella
Shigella
Staphylococcus
Streptococcus
Vibrio
Yersinia
Download

 
Vibrio


General information:
Gram-negative, part of the family Vibrionaceae, which is also includes the genera Aeromonas and Plesiomonas
V. cholerae is one of several medically important species, the others being V. parahaemolyticus and V. vulnificus
Characteristics:
V. cholerae is well recoginzed and extensively studied as the causative agent of the human intestinal disease cholera. The disease occurs at the mucosal surface, with no invasion by the microbe into deeper tissue, and the disease symptons are primarily due to the action of a sigle molecule, the cholera toxin
Disease:
Cholera
Genomes (comparative pathogenomics):
V. cholerae O1 biovar El Tor str. N16961 chromosome I, 2961149 bp, NC_002505
V. cholerae O1 biovar El Tor str. N16961 chromosome II, 1072315 bp, NC_002506
V. cholerae O395 chromosome 1, 1108250 bp, NC_009456
V. cholerae O395 chromosome 2, 3024069 bp, NC_009457
V. fischeri ES114 chromosome I, 2897536 bp, NC_006840
V. fischeri ES114 chromosome II, 1330333 bp, NC_006841
V. harveyi ATCC BAA-1116 chromosome II, 2204018 bp, NC_009784
V. parahaemolyticus RIMD 2210633 chromosome 1, 3288558 bp, NC_004603
V. parahaemolyticus RIMD 2210633 chromosome 2, 1877212 bp, NC_004605
V. vulnificus CMCP6 chromosome I, 3281866 bp, NC_004459
V. vulnificus CMCP6 chromosome II, 1844830 bp, NC_004460
V. vulnificus YJ016 chromosome I, 3354505 bp, NC_005139
V. vulnificus YJ016 chromosome II, 1857073 bp, NC_005140
Publications:
Heidelberg JF, et al., 2000. DNA sequence of both chromosomes of the cholera pathogen Vibrio cholerae Nature 406(6795):477-483.
Feng L, et al., 2008. A recalibrated molecular clock and independent origins for the cholera pandemic clones. PLoS One 3(12):e4053.
Ruby EG, et al., 2005. Complete genome sequence of Vibrio fischeri: a symbiotic bacterium with pathogenic congeners. Proc. Natl. Acad. Sci. USA 102(8):3004-3009.
Makino K, et al., 2003. Genome sequence of Vibrio parahaemolyticus: a pathogenic mechanism distinct from that of V. cholerae Lancet 361(9359):743-749.
Kim YR, et al., 2003. Characterization and pathogenic significance of Vibrio vulnificus antigens preferentially expressed in septicemic patients. Infect Immun 71(10):5461-5471.
Chen CY, et al., 2003. Comparative genome analysis of Vibrio vulnificus, a marine pathogen. Genome Res. 13(12):2577-2587.
Figures:

Major virulence factors in Vibrio:
Adherence
ACF
IlpA (V. vulnificus)
MAM7 (V. parahaemolyticus)
MSHA pili
OmpU (V. vulnificus)
TCP
VpadF (V. parahaemolyticus)
Motility
Flagella
Regulation
AI-2
CAI-1
Secretion system
T3SS1 (V. parahaemolyticus)
T3SS2 (V. parahaemolyticus)
T6SS
Toxin
Ace
CT
MARTX
TDH (V. parahaemolyticus)
TRH (V. parahaemolyticus)
VCC
Zot
Pathogenicity islands in Vibrio:
VPI
VPI-2
Location of virulence-associated genes in V. cholerae:
View the legend

View the legend


Back to Top
Back to Top