|
| Type IV secretion system |
 |
A pilus-like structure crossing the inner and outer membrane of the bacterium and like a needle inserts into the membrane of host cell. ... |
|
| T6SS |
|
Type VI bacterial lipase/phospholipase effectors (Tle) has been sub-divided into Tle1–Tle5. The Tle1–Tle4 families exhibit the GXSXG motif, while Tle5 present a dual HXKXXXXD motif. ... |
|
Dot/Icm
(Defect in organella trafficking/intracellular multiplication) |
|
14 genes share detectable homology to the tra/trb genes of col1b-P9 plasmid, a member of the IncI class of conjugal plasmids. The second type IV secretion apparatus lvh (Legionella vir homologs) system is poorly characterized. Its 11 genes are located on a genomic-island-like region. It might play a role in the efficiency of host cell infection by L. pneumophila grown at lower temperatures. However, the specific substrates of this system have not yet been identified. ... |
|
lsp T2SS
(Type II secretion system) |
|
This secretion system is encoded on 5 regions scattered over the chromosome in contrast to most other bacteria where the type II genes are clustered in one or two regions. ... |
|
ESX-1
(ESAT-6 secretion system-1) |
|
The ESX-1 secretion system is encoded by two different loci, the ESX-1 locus and the EspA operon. The exact number of components that are involved in ESX-1 secretion is still debated and seems to vary between different mycobacterial species. All the known ESX-1 substrates, Rv3616c(EspA), Rv3615c, ESAT-6 and CFP-10 are mutually dependent on each other for secretion. ... |
|
| ESX-3 |
|
Required for siderophore-mediated iron acquisition. ... |
|
ESX-5
(ESAT-like secretion system) |
|
Essential for the secretion of the ESX-5-encoded ESAT-6-family member EsxN by M. marinum. Necessary and sufficient to produce a functional secretion machinery for PPE41 in M. smegmatis. ... |
|
HSI-1
(Hcp secretion island I) |
|
HSI-1 is highly homologous to a group of genes found in many Gram-negative proteobacteria that have been termed the IcmF-associated homologous protein (IAHP) cluster and encodes a secretory system that may play a general role in mediating host interaction. ... |
|
| HSI-2 |
|
P. aeruginosa encodes three distinct T6SS loci, H1- to H3-T6SS. While H1-T6SS has only been involved in antibacterial activity so far, H2-T6SS and H3-T6SS can target both bacterial and eukaryotic cells possessing even as said earlier trans-kingdom effectors. ... |
|
| HSI-3 |
|
The expression of T6SSs in P. aeruginosa is regulated by the QS system. There are several QS systems in P. aeruginosa, two N-acyl-homoserine lactone based QS systems (las and rhl systems) and one quinolone PQS system (pqs). The expression of H1-T6SS is negatively regulated by both las and pqs QS systems, while the expression of H2- and H3-T6SS is positively regulated by las, rhl, and pqs. ... |
|
| | | |
