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Cwp66
(Cell wall protein 66) |
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Binding to host cells is induced by heat shock. ... |
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CwpV
(Cell wall protein V) |
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CwpV is the largest member of the CWP family and consists of three distinct domains: (1) an N-terminal region with putative cell wall binding activity, (2) a region of unknown function terminating in a serine-glycine-rich flexible linker, (3) C-terminal domain. Five different types of CwpV have been described to date, each differing in its C-terminal domain. The characteristic feature of this domain is the presence of 4~9 tandem repeats of amino acids, each repeat comprising between 79 and 120 amino acids. ... |
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FbpA/Fbp68
(Fibronectin-binding protein A) |
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Fibronectin is a dimeric glycoprotein (~440 kDa) which is present in a soluble form in plasma and in an immobilized form on cell surfaces and in extracellular matrix. It is an important target for bacterial attachment in many pathogens, such as S. pyogenes, S. pneumoniae and L. monocytogenes, where fibronectin-binding proteins are important virulence factors. ... |
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| GroEL |
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GroEL of numerous bacteria, such as L. pneumophila, H. pylori, H. ducreyi, M. avium, S. typhimurium, A. actinomycetemcomitans and B. burgdorferi, has been shown to be involved in adhesion or invasion of various target cells or tissues. ... |
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SlpA
(S-layer protein A) |
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S-layers have been observed in hundreds of prokaryotic species, including a diverse range of bacteria and virtually all archaea. A typical S-layer consists of a single protein arranged in a two dimensional paracrystalline array, forming the outermost surface of the cell. The majority of the C. difficile S-layer is formed by the low and high molecular weight S-layer proteins (LMW SLP and HMW SLP) which are coded by a single gene slpA. HMW SLP binds to the cell wall through a non-covalent interaction, while LMW SLP is presented as the outermost surface of the cell. ... |
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| CdiLAM |
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The genus Corynebacterium is part of the phylogenetic group nocardioform actinomycetes. The cell wall of C. diphtheriae is composed of branched long-chain mycolic acids and other lipoglycans such as lipomannans (LM) and lipoarabinomannans (LAM). Mannose-capped LAM (ManLAM) from M. tuberculosis may facilitate bacterial adherence to alveolar macrophages, particularly to mannose receptors and display immunomodulatory properties. ... |
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| DIP0733 |
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Composed of seven transmembrane helices and a hydrophilic region. C-terminal coiled-coil domain is important for the binding to Type I collagen and fibrinogen. ... |
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| DIP1281 |
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Surface-associated protein belongs to NlpC/P60 family. Involved in cell surface organization, adhesion and internalization in epithelial cells. ... |
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| DIP1621 |
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Surface-associated protein belongs to NlpC/P60 family. Play a role in adhesion to epithelial cells. ... |
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| DIP2093 |
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Structural similarity to SdrD protein from S. aureus, which plays an important role in the adherence of S. aureus to the ECM and in biofilm formation. ... |
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