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| HbhA |
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Surface-located protein. A multifunctional protein involved in adherence of Mycobacterium tuberculosis to non-phagocytic cells and in the formation of intracytosolic lipid inclusions. ... |
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| Cytadherence organelle |
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Only mycoplasmas within the same phylogenic group as M. pneumoniae and M. gallisepticum possess a homologous structure, or orthologous of the genes responsible. ... |
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| P97/P102 paralog family |
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Including P97 (mhp183), P102 (mhp182), P97 paralogs (mhp107, mhp493, mhp271, mhp385) and P102 paralogs (mhp683, mhp384). ... |
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| RTX protein |
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Many RTX proteins serve as major virulence factors of Gram-negative pathogens. These large, multidomain proteins share a common architecture comprised of four regions. First, C teminal end leading is the RTX export sequence that directs the protein through the T1SS. This is followed by the ligand-binding region responsible for host adhesion and cohesion, which contains diverse ligand-binding domains. Thereaftert is a large extension region consisting of tens to hundreds of tandem bacterial immunoglobulin-like domains. Lastly, there is a conserved N terminal cell-membrane-anchor region. ... |
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rOmpA/Sca0
(Surface cell antigen 0) |
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Conserved throughout the spotted fever group. Studies have suggested that rOmpA plays a role in adhesion, but recent studies indicate that rOmpA is not critical for virulence in a guinea pig model but may play a role in survival or transmission from the tick vector. ... |
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Sca1
(Surface cell antigen 1) |
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Mediates adhesion to various types of epithelial and endothelial cells. ... |
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| MisL |
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An N-terminal signal peptide, an internal passenger domain, and a C-terminal translocator domain. MisL is an extracellular matrix adhesin involved in intestinal colonization. ... |
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| RatB |
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Three putative intestinal colonization factors SinH, RatB and ShdA, are located in the same 25-kb pathogenicity island, called CS54. This island is present only in subspecies 1 of S. enterica. ... |
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| ShdA |
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ShdA passenger domain consists of ~1,500 amino acid residues that can be divided into two regions based on features of the primary amino acid sequence: an N-terminal nonrepeat region followed by a repeat region composed of two types of imperfect direct amino acid repeats, called type A and type B. The repeat region bound fibronectin with an affinity similar to that for the complete ShdA passenger domain. ... |
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| SinH |
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N-terminal 350 residues exhibits homology with invasin of Yersinia pseudotuberculosis (49.5% identity) and intimin of E. coli O111 (enteropathogenic E. coli) (48% identity). The amino termini of invasin and intimin serve as membrane-spanning anchors in the bacterial outer membrane. ... |
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