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VF category: Adherence (total 2070 related VFs in database, current show from 21 to 30)
 
VF Bacteria Brief description
Fap
(Functional amyloid in Pseudomonas)
Pseudomonas
(P. aeruginosa PAO1)
The Fap system displays many similarities to the curli system, but the two are not evolutionary related. ...
Type IV pili
Pseudomonas
(P. aeruginosa PAO1)
pilA, B, C, D, E, F, M, N, O, P, Q, T, U, V, W, X, Y1, Y2, Z, and fimT, U, V are involved in the biogenesis and mechanical function of pili, pilG, H, I, K, chpA, B, C, D, E, pilS, R, fimS, rpoN, algR, algU, and vfr are involved in transcriptional regulation and chemosensory pathways that control the expression or activity of the twitching motility of the pili. ...
Agf
(Thin aggregative fimbriae (or curli))
Salmonella
(S. enterica subsp. enterica serovar Typhimurium str. LT2)
Homology to csg of E.coli. Nucleator-dependent assembly pathway. Aids in attachment to the villi of enterocytes, also cause the bacteria to become attached to each other. ...
Lpf
(Long polar fimbriae)
Salmonella
(S. enterica subsp. enterica serovar Typhimurium str. LT2)
Chaperone-usher assembly pathway. Mediate attachment to the Peyer's patches. ...
Pef
(Plasmid-encoded fimbriae)
Salmonella
(S. enterica subsp. enterica serovar Typhimurium str. LT2)
Chaperone-usher assembly pathway. Mediate binding of the bacteria to the microvilli of enterocytes. ...
Type 1 fimbriae
Salmonella
(S. enterica subsp. enterica serovar Typhimurium str. LT2)
Chaperone-usher assembly pathway. The adhesin FimH mediates T3SS1-independent uptake in murine DCs. ...
GAS pili
Streptococcus
(S. pyogenes MGAS5005)
The GAS pili are encoded in the variable FCT (fibronectin- and collagen-binding T-antigen) region. The C-terminal domain of Cpa, residues 286–723, mediates its adhesive properties and contains three domains: the middle domain (residues 291–372 and 590–597), the top domain (residues 390–583) and the bottom domain (residues 603–719). The middle domain and the bottom domain each adopt an Ig-like all- fold with an intramolecular isopeptide bond involving residues Lys297 and Asp595 in the middle domain and residues Lys610 and Asn715 in the bottom domain, similar to those found in other pilins. ...
PI-2
Streptococcus
(S. pneumoniae Taiwan19F-14)
The type PI-2 streptococcal pilus presents in a number of invasive pneumococcal serotypes and consists of repeated units of a single protein, PitB, whose covalent association is catalyzed by cognate sortase SrtG-1 and partner protein SipA. ...
rlrA islet
Streptococcus
(S. pneumoniae TIGR4)
Pili are encoded by the rlrA pathogenicity islet, which carries genes for three pilin proteins (the major pilin RrgB and two minor pilins, RrgA and RrgC, RrgA is the tip adhesin) as well as three sortases. ...
Myf/pH6 antigen
(Mucoid Yersinia factor)
Yersinia
(Y. pestis CO92)
Myf in Y.enterocolitica and its homolog pH 6 antigen in Y.pestis and Y.pseudotuberculosis. Belongs to a class of adhesins that are secreted/assembled via a so-called chaperone/usher pathway: myfA/psaA encodes the main fibriallar subunit, myfB/psaB and myfC/psaC are required for transport of the subunit across the bacterial membrane and assembly of the subunit into fibrillae, MyfB/PsaB is a member of the PapB family of periplasmic chaperones and could act as a chaperone for MyfA/PsaA, while MyfC/PsaC could act as an usher in the outer membrane. MyfE/PsaE and MyfF/PsaF (two component) are required for transcription of myfA/psaA. ...
   


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