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CNF-1
(Cytotoxic necrotizing factor 1) |
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Expressed by certain uropathogenic and neonatal meningitis-causing strains of E. coli. Belongs to a unique group of large cytotoxins that cause constitutive activation of Rho GTPase. Two types (CNF-1 and CNF-2) have 90% conserved residues over 1014-amino-acid sequences and share the same catalytic activity. CNF1 is encoded by the chromosome, whereas a transmissible plasmid called pVir codes for CNF2. ... |
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CNF-1
(Cytotoxic necrotizing factor 1) |
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Expressed by certain uropathogenic and neonatal meningitis-causing strains of E. coli. Belongs to a unique group of large cytotoxins that cause constitutive activation of Rho GTPase. Two types (CNF-1 and CNF-2) have 90% conserved residues over 1014-amino-acid sequences and share the same catalytic activity. CNF1 is encoded by the chromosome, whereas a transmissible plasmid called pVir codes for CNF2. ... |
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CNF-1
(Cytotoxic necrotizing factor 1) |
|
Expressed by certain uropathogenic and neonatal meningitis-causing strains of E. coli. Belongs to a unique group of large cytotoxins that cause constitutive activation of Rho GTPase. Two types (CNF-1 and CNF-2) have 90% conserved residues over 1014-amino-acid sequences and share the same catalytic activity. CNF1 is encoded by the chromosome, whereas a transmissible plasmid called pVir codes for CNF2. ... |
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CNF-1
(Cytotoxic necrotizing factor 1) |
|
Expressed by certain uropathogenic and neonatal meningitis-causing strains of E. coli. Belongs to a unique group of large cytotoxins that cause constitutive activation of Rho GTPase. Two types (CNF-1 and CNF-2) have 90% conserved residues over 1014-amino-acid sequences and share the same catalytic activity. CNF1 is encoded by the chromosome, whereas a transmissible plasmid called pVir codes for CNF2. ... |
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| Heat-labile toxin (LT) |
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Secreted to the extracellular milieu by a type II secretion system. LT-I is plasmid-encoded. LT-II only produced by strains isolated from animals. ... |
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| Heat-labile toxin (LT) |
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Secreted to the extracellular milieu by a type II secretion system. LT-I is plasmid-encoded. LT-II only produced by strains isolated from animals. ... |
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| Heat-labile toxin (LT) |
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Secreted to the extracellular milieu by a type II secretion system. LT-I is plasmid-encoded. LT-II only produced by strains isolated from animals. ... |
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Stx
(Shiga toxin) |
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Also known as verotoxin, verocytotoxin or Shiga-like toxins, are produced by several enteric pathogens, most importantly Shigella dysenteriae (serotype 1 only) and EHEC. The Stx family contains two subgroups: Stx1 and Stx2, that share approximately 55% amino acid homology. Retrograde transport to the ER via a Rab6-dependent pathway. ... |
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Stx
(Shiga toxin) |
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Also known as verotoxin, verocytotoxin or Shiga-like toxins, are produced by several enteric pathogens, most importantly Shigella dysenteriae (serotype 1 only) and EHEC. The Stx family contains two subgroups: Stx1 and Stx2, that share approximately 55% amino acid homology. Retrograde transport to the ER via a Rab6-dependent pathway. ... |
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Stx
(Shiga toxin) |
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Also known as verotoxin, verocytotoxin or Shiga-like toxins, are produced by several enteric pathogens, most importantly Shigella dysenteriae (serotype 1 only) and EHEC. The Stx family contains two subgroups: Stx1 and Stx2, that share approximately 55% amino acid homology. Retrograde transport to the ER via a Rab6-dependent pathway. ... |
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