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Hpt (Hexose phosphate transporter) |
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Belongs to the organophosphate:inorganic phosphate antiporter (OPA) family, of the major facilitator superfamily of permease. Hpt is the first virulence factor to be identified as specifically involved in the replication phase of a facultative intracellular pathogen. It could be termed "metabolic" virulence factor and represent an example of the concept in the biology of host-pathogen interaction: adaptation to parasitic life often involves the mimicry of eukaryotic host functions by microbial virulence factors. Expression of the Hpt permease is tightly cotrolled by the PrfA. ... |
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Hpt (Hexose phosphate transporter) |
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Belongs to the organophosphate:inorganic phosphate antiporter (OPA) family, of the major facilitator superfamily of permease. Hpt is the first virulence factor to be identified as specifically involved in the replication phase of a facultative intracellular pathogen. It could be termed "metabolic" virulence factor and represent an example of the concept in the biology of host-pathogen interaction: adaptation to parasitic life often involves the mimicry of eukaryotic host functions by microbial virulence factors. Expression of the Hpt permease is tightly cotrolled by the PrfA. ... |
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Hpt (Hexose phosphate transporter) |
|
Belongs to the organophosphate:inorganic phosphate antiporter (OPA) family, of the major facilitator superfamily of permease. Hpt is the first virulence factor to be identified as specifically involved in the replication phase of a facultative intracellular pathogen. It could be termed "metabolic" virulence factor and represent an example of the concept in the biology of host-pathogen interaction: adaptation to parasitic life often involves the mimicry of eukaryotic host functions by microbial virulence factors. Expression of the Hpt permease is tightly cotrolled by the PrfA. ... |
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Hpt (Hexose phosphate transporter) |
|
Belongs to the organophosphate:inorganic phosphate antiporter (OPA) family, of the major facilitator superfamily of permease. Hpt is the first virulence factor to be identified as specifically involved in the replication phase of a facultative intracellular pathogen. It could be termed "metabolic" virulence factor and represent an example of the concept in the biology of host-pathogen interaction: adaptation to parasitic life often involves the mimicry of eukaryotic host functions by microbial virulence factors. Expression of the Hpt permease is tightly cotrolled by the PrfA. ... |
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Hpt (Hexose phosphate transporter) |
|
Belongs to the organophosphate:inorganic phosphate antiporter (OPA) family, of the major facilitator superfamily of permease. Hpt is the first virulence factor to be identified as specifically involved in the replication phase of a facultative intracellular pathogen. It could be termed "metabolic" virulence factor and represent an example of the concept in the biology of host-pathogen interaction: adaptation to parasitic life often involves the mimicry of eukaryotic host functions by microbial virulence factors. Expression of the Hpt permease is tightly cotrolled by the PrfA. ... |
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Hpt (Hexose phosphate transporter) |
|
Belongs to the organophosphate:inorganic phosphate antiporter (OPA) family, of the major facilitator superfamily of permease. Hpt is the first virulence factor to be identified as specifically involved in the replication phase of a facultative intracellular pathogen. It could be termed "metabolic" virulence factor and represent an example of the concept in the biology of host-pathogen interaction: adaptation to parasitic life often involves the mimicry of eukaryotic host functions by microbial virulence factors. Expression of the Hpt permease is tightly cotrolled by the PrfA. ... |
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Hpt (Hexose phosphate transporter) |
|
Belongs to the organophosphate:inorganic phosphate antiporter (OPA) family, of the major facilitator superfamily of permease. Hpt is the first virulence factor to be identified as specifically involved in the replication phase of a facultative intracellular pathogen. It could be termed "metabolic" virulence factor and represent an example of the concept in the biology of host-pathogen interaction: adaptation to parasitic life often involves the mimicry of eukaryotic host functions by microbial virulence factors. Expression of the Hpt permease is tightly cotrolled by the PrfA. ... |
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Hpt (Hexose phosphate transporter) |
|
Belongs to the organophosphate:inorganic phosphate antiporter (OPA) family, of the major facilitator superfamily of permease. Hpt is the first virulence factor to be identified as specifically involved in the replication phase of a facultative intracellular pathogen. It could be termed "metabolic" virulence factor and represent an example of the concept in the biology of host-pathogen interaction: adaptation to parasitic life often involves the mimicry of eukaryotic host functions by microbial virulence factors. Expression of the Hpt permease is tightly cotrolled by the PrfA. ... |
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Hpt (Hexose phosphate transporter) |
|
Belongs to the organophosphate:inorganic phosphate antiporter (OPA) family, of the major facilitator superfamily of permease. Hpt is the first virulence factor to be identified as specifically involved in the replication phase of a facultative intracellular pathogen. It could be termed "metabolic" virulence factor and represent an example of the concept in the biology of host-pathogen interaction: adaptation to parasitic life often involves the mimicry of eukaryotic host functions by microbial virulence factors. Expression of the Hpt permease is tightly cotrolled by the PrfA. ... |
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LipF |
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Annotated as a lipase/esterase, dramatically upregulated at low pH, a possible function of lipF could be to hydrolyze toxic fatty acids present in caseous necrotic debris during tuberculosis or it may modify the external cell wall as an adaptive response to acid damage. ... |
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