The trimeric autotransporter adhesin Yersinia adhesin A is the prototype of the type Vc secretion system. Present in the virulence plasmids of Y. enterocolitica and Y. pseudotuberculosis. The yadA gene of Y. pestis is inactivated by frameshift. Homotrimeric protein belongs to the family of lollipop-shaped adhesins, with a globular head domain, a rigid stalk domain and a C-teriminal membrane anchor. ...
YapE requires proteolytic cleavage by the omptin Pla (plasminogen activator protease). Y. pestis YapE is required to mediate bacterial aggregation and adherence to eukaryotic cells. ...
Acts as an adhesin for alveolar epithelial cells and specific extracellular matrix (ECM) proteins. Recruits mammalian neural Wiskott-Aldrich syndrome protein (N-WASP). ...