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VF category: Type III secretion system (T3SS) (total 248 related VFs in database, current show from 71 to 80)
 
VF Bacteria Brief description
Efa-1/LifA
(EHEC factor for adherence/lymphocyte inhibitory factor)
Escherichia
(E. coli O157:H7 str. EDL933)
 Inhibits lymphocyte activation. Acting as adhesin in non-O157:H7 EHEC strains. ...
Efa-1/LifA
(EHEC factor for adherence/lymphocyte inhibitory factor)
Escherichia
(E. coli O26:H11 str. 11368)
 Inhibits lymphocyte activation. Acting as adhesin in non-O157:H7 EHEC strains. ...
Lymphostatin/LifA
Escherichia
(E. coli O127:H6 str. E2348/69)
 Encoded outside the LEE. Very large protein of ~385 kDa. Contains sequence similarity to the glycosyltransferase region of the large clostridial cytotoxins. Also present in strains of EHEC, where it is known as Efa1. ...
ToxB
Escherichia
(E. coli O157:H7 str. EC4115)
 A large 362-kDa protein encoded on the 93-kb plasmid that is present in O157:H7 and other EHEC strains. Shares sequence similarity with the large Clostridium toxin family, and to the Efa-1/LifA protein. ...
ToxB
Escherichia
(E. coli O157:H7 str. Sakai)
 A large 362-kDa protein encoded on the 93-kb plasmid that is present in O157:H7 and other EHEC strains. Shares sequence similarity with the large Clostridium toxin family, and to the Efa-1/LifA protein. ...
ToxB
Escherichia
(E. coli O157:H7 str. TW14359)
 A large 362-kDa protein encoded on the 93-kb plasmid that is present in O157:H7 and other EHEC strains. Shares sequence similarity with the large Clostridium toxin family, and to the Efa-1/LifA protein. ...
ToxB
Escherichia
(E. coli O26:H11 str. 11368)
 A large 362-kDa protein encoded on the 93-kb plasmid that is present in O157:H7 and other EHEC strains. Shares sequence similarity with the large Clostridium toxin family, and to the Efa-1/LifA protein. ...
ToxB
Escherichia
(E. coli O157:H7 str. Xuzhou21)
 A large 362-kDa protein encoded on the 93-kb plasmid that is present in O157:H7 and other EHEC strains. Shares sequence similarity with the large Clostridium toxin family, and to the Efa-1/LifA protein. ...
TTSS
(Type III secretion system)
Escherichia
(E. coli O103:H2 str. 12009)
 Encoded on the pathogenicity island known as the locus of enterocyte effacement (LEE). Injects Tir and other effector molecules directly into the host cell. Effector molecules activate cell-signaling pathways, causing alterations in the host cell cytoskeleton and resulting in the depolymerization of actin and the loss of microvilli. ...
TTSS
(Type III secretion system)
Escherichia
(E. coli O111:H- str. 11128)
 Encoded on the pathogenicity island known as the locus of enterocyte effacement (LEE). Injects Tir and other effector molecules directly into the host cell. Effector molecules activate cell-signaling pathways, causing alterations in the host cell cytoskeleton and resulting in the depolymerization of actin and the loss of microvilli. ...
   


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