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VF category: Gram+ heme acquisition system (total 27 related VFs in database, current show from 1 to 10)
 
VF Bacteria Brief description
Isd
Staphylococcus
(S. aureus subsp. aureus str. Newman)
Surface exposed protein glyceraldehyde-3-phosphate dehydrogenase (GAPDH), an enzyme usually associated with glycolysis, is a transferrin receptor involved in stripping iron off transferrin. isd genes (iron-regulated surface determinant) encode factors for hemoglobin binding and passage of heme-iron to the cytoplasm:. Hemoglobin binds on IsdB. Heme is removed from hemoglobin (IsdA and IsdB) and transferred to cell wall (IsdC) and membrane translocation factors (IsdD, IsdE and IsdF). IsdG is involved in removing iron from heme. S. aureus also has a siderophore-based mechanism for iron acquisition. ...
Hal
(Heme-acquisition leucine-rich repeat protein)
Bacillus
(B. anthracis str. Sterne)
Includes an N-terminal near-iron transporter (NEAT) domain, several internal leucine-rich repeat (LRR) regions, and a C-terminal sortase-like cell wall anchor. ...
IlsA
(Iron-regulated leucine rich surface protein type A)
Bacillus
(B. cereus ATCC 10987)
The three conserved domains: NEAT (NEAr iron Transporter), LRR (Leucine-Rich Repeat) and SLH (Surface Layer Homology). Specifically expressed in the insect hemocoel and under iron-depleted conditions. ...
Hal
(Heme-acquisition leucine-rich repeat protein)
Bacillus
(B. anthracis str. Ames)
Includes an N-terminal near-iron transporter (NEAT) domain, several internal leucine-rich repeat (LRR) regions, and a C-terminal sortase-like cell wall anchor. ...
Hal
(Heme-acquisition leucine-rich repeat protein)
Bacillus
(B. anthracis str. Ames Ancestor)
Includes an N-terminal near-iron transporter (NEAT) domain, several internal leucine-rich repeat (LRR) regions, and a C-terminal sortase-like cell wall anchor. ...
Hal
(Heme-acquisition leucine-rich repeat protein)
Bacillus
(B. cereus AH187)
Includes an N-terminal near-iron transporter (NEAT) domain, several internal leucine-rich repeat (LRR) regions, and a C-terminal sortase-like cell wall anchor. ...
Hal
(Heme-acquisition leucine-rich repeat protein)
Bacillus
(B. cereus ATCC 10987)
Includes an N-terminal near-iron transporter (NEAT) domain, several internal leucine-rich repeat (LRR) regions, and a C-terminal sortase-like cell wall anchor. ...
Hal
(Heme-acquisition leucine-rich repeat protein)
Bacillus
(B. cereus ATCC 14579)
Includes an N-terminal near-iron transporter (NEAT) domain, several internal leucine-rich repeat (LRR) regions, and a C-terminal sortase-like cell wall anchor. ...
Hal
(Heme-acquisition leucine-rich repeat protein)
Bacillus
(B. cereus biovar anthracis str. CI)
Includes an N-terminal near-iron transporter (NEAT) domain, several internal leucine-rich repeat (LRR) regions, and a C-terminal sortase-like cell wall anchor. ...
Hal
(Heme-acquisition leucine-rich repeat protein)
Bacillus
(B. cereus E33L)
Includes an N-terminal near-iron transporter (NEAT) domain, several internal leucine-rich repeat (LRR) regions, and a C-terminal sortase-like cell wall anchor. ...
   


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