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VF category: T2SS components (total 38 related VFs in database, current show from 1 to 10)
 
VF Bacteria Brief description
T2SS
Acinetobacter
(A. baumannii ACICU)
Although the T2SS machinery is conserved across Acinetobacter spp., the effector repertoire is diverse and varies from strain to strain. Secretion of type II effectors, CpaA and LipA, require specific membrane-associated chaperones, CpaB and LipB. ...
Exe T2SS
Aeromonas
(A. hydrophila ML09-119)
Essential for secretion of many virulence factors, such as aerolysin, proteases, haemolysin and DNase. ...
lsp T2SS
(Type II secretion system)
Legionella
(L. pneumophila subsp. pneumophila str. Philadelphia 1)
This secretion system is encoded on 5 regions scattered over the chromosome in contrast to most other bacteria where the type II genes are clustered in one or two regions. ...
T2SS
(Type II secretion system)
Shigella
(S. dysenteriae Sd197)
T2SS encoded by genes of the general secretion pathway (gsp) is widely distributed in Gram-negative bacteria. The known E.coli T2SS, responsible for chitinase secretion, encoded by the yhe genes at 74.5 min of the MG1655 chromosome is absent in all four sequenced Shigella genomes. A novel set of gsp genes are located on the S. dysenteriae Sd197 and S. boydii Sb227 chromosomes. The Sb227 T2SS is likely to be inactive due to a frameshift in gspC and a nonsense mutation in gspD. Those genes show significant similarity to those from ETEC and Vibrio cholerae responsible for secreting the E.coli heat labile toxin (Ltx) and cholera toxin (Ctx), respectively. While Shiga toxin has an overall similar structure to Ctx and Ltx. ...
Eps T2SS
(Extracellular protein secretion)
Vibrio
(V. cholerae O395)
V. cholerae causes diarrhea by T2SS-dependent secretion of cholera toxin. V. cholerae exports, via the T2SS, other extracellular factors, including chitinases, proteases, DNase, and pilin, which aid in its ability to successfully occupy diverse ecological niches. Eps T2SS also secretes the three proteins RbmA, RbmC, and Bap1, which are necessary for robust, shear-resistant biofilm formation. ...
Yst1 T2SS
(Yst1 type II secretion system)
Yersinia
(Y. enterocolitica subsp. enterocolitica 8081)
The Yts1 T2SS seems to be present in all high-pathogenicity Y. enterocolitica species (serotypes O:8, O:13, O:20, O:21) but not in low-pathogenic Y. enterocolitica isolates (e.g., O:3, O:9). ...
T2SS
Acinetobacter
(A. baumannii 1656-2)
Although the T2SS machinery is conserved across Acinetobacter spp., the effector repertoire is diverse and varies from strain to strain. Secretion of type II effectors, CpaA and LipA, require specific membrane-associated chaperones, CpaB and LipB. ...
T2SS
Acinetobacter
(A. baumannii AB0057)
Although the T2SS machinery is conserved across Acinetobacter spp., the effector repertoire is diverse and varies from strain to strain. Secretion of type II effectors, CpaA and LipA, require specific membrane-associated chaperones, CpaB and LipB. ...
T2SS
Acinetobacter
(A. baumannii ATCC 17978)
Although the T2SS machinery is conserved across Acinetobacter spp., the effector repertoire is diverse and varies from strain to strain. Secretion of type II effectors, CpaA and LipA, require specific membrane-associated chaperones, CpaB and LipB. ...
T2SS
Acinetobacter
(A. baumannii AYE)
Although the T2SS machinery is conserved across Acinetobacter spp., the effector repertoire is diverse and varies from strain to strain. Secretion of type II effectors, CpaA and LipA, require specific membrane-associated chaperones, CpaB and LipB. ...
   


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