The gene encoding the hemoglobin receptor, hmbR, is located downstream of a gene involved in the catabolism of heme, hemO. Expression of HmbR undergoes phase variation due to slip-strand mispairing of poly(G) tracts within the hmbR gene. The advantage associated with phase-varying surface proteins is evasion of the host immune response. ...
Current studies show the hemO gene cluster is required for optimal utilization of heme in A. baumannii hypervirulent strains. The hemO gene cluster encodes a secreted hemophore. ...
Current studies show the hemO gene cluster is required for optimal utilization of heme in A. baumannii hypervirulent strains. The hemO gene cluster encodes a secreted hemophore. ...
Current studies show the hemO gene cluster is required for optimal utilization of heme in A. baumannii hypervirulent strains. The hemO gene cluster encodes a secreted hemophore. ...
Current studies show the hemO gene cluster is required for optimal utilization of heme in A. baumannii hypervirulent strains. The hemO gene cluster encodes a secreted hemophore. ...