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VF category: Immune modulation (total 1613 related VFs in database, current show from 51 to 60)
 
VF Bacteria Brief description
NspA
(Neisserial surface protein A)
Neisseria
(N. meningitidis MC58)
PDB code: 1P4T. Binds complement factor H to inhibit host innate immune defenses. ...
Rhamnolipid
Pseudomonas
(P. aeruginosa PAO1)
Nonenzyme glycolipid. Mainly acylated rhamnose moieties synthesized by four enzymes using substrates derived from fatty acid biosynthesis and thymidine-diphospho-L-rhamnose. ...
Adr1
(Adhesion of Rickettsiae protein 1)
Rickettsia
(R. typhi str. Wilmington)
An integral outer-membrane protein containing eight membrane-embedded β-strands and four "loop" regions that are exposed to extracellular milieu. Belongs to a family of gram-negative outer membrane proteins embodied by E. coli OmpX. Some members of this protein family, namely Yersinia enterolitica Ail and Salmonella typhimurium Rck. ...
Adr2
(Adhesion of Rickettsiae protein 2)
Rickettsia
(R. typhi str. Wilmington)
In all Rickettsia genomes, two Adr paralogs are encoded adjacent to one another and share ~45% aa identity. ...
Rck
(Resistance to complement killing)
Salmonella
(S. enterica subsp. enterica serovar Typhimurium str. LT2)
Rck belongs to a family of five homologous OMP proteins characterized in Salmonella (Rck and PagC), Escherichia coli (Lom), Yersinia enterocolitica (Ail) and Enterobacter cloacae (OmpX). ...
LPS
Shigella
(S. flexneri 2a str. 301)
Composed of the O-antigen, core polysaccharides and lipid A. The genes involved in the biosynthesis of the basic O-antigen are located in the rfb/rfc loci. O-antigen modification is associated with temperate bacteriophages. Four different serotype-converting phages have been found: SfII, Sf6, SfV and SfX, which are involved in conversion of a serotype Y stain to serotypes 2a, 3b, 5a and X, respectively. ...
AdsA
(Adenosine synthase A)
Staphylococcus
(S. aureus subsp. aureus MW2)
Harbors two 5'-nucleotidase motifs and a C-terminal LPXTG motif sorting signal. Evasion from innate immunity. ...
CHIPS
(Chemotaxis inhibitory protein of Staphylococcus)
Staphylococcus
(S. aureus subsp. aureus str. Newman)
Located on the β-hemolysin (hlb)-converting bacteriophages. Evasion from innate immunity. ...
Sbi
(Staphylococcal binder of immunoglobulin)
Staphylococcus
(S. aureus subsp. aureus MW2)
A secreted protein that is also associated with the bacterial envelope, lacks a C-terminal LPXTG sorting signal. ...
SCIN
(Staphylococcal complement inhibitor)
Staphylococcus
(S. aureus subsp. aureus MW2)
Located on the β-hemolysin (hlb)-converting bacteriophages. Evasion from innate immunity. ...
   


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