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| Rvh T4SS |
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Similar to the virB/virD system of A. tumefaciens. The T4SS of Rickettsiales is characterized by an expansion of the virB4 and virB6 gene families and an absence of virB5. In addition, species in the family Anaplasmataceae have an expansion of virB2 and are missing virB1. The presence of multiple copies of T4SS components may facilitate environment- or host cell-dependent delivery of effector molecules. ... |
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| Trw type IV secretion system |
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The Trw system of Bartonella, probably acquired from horizontal gene transfer, shares an extensive homology with the Trw system of the Trw conjugation machinery of the broad-host-range antibiotic-resistance plasmid R388. The trw genes of Bartonella are collinear with the respective genes of plasmid R388, except for the presence of multiple tandem gene duplications of trwL and trwJIH in Bartonella. The trwL (the homologue of the pilin virB2) and trwJ (the homologues of the minor pilus-associated component virB5) sequences are highly variable within the same Bartonella species, as well as between different species. But the various copies of trwH and trwI are almost identical. A remarkable difference between Trw systems of plasmid R388 and of Bartonella is the lack of the T4CP-encoding trwB gene in Bartonella. ... |
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| VirB/VirD4 type IV secretion system |
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The VirB/VirD4 T4SS is well conserved within the genus Bartonella, although it is absent in B. bacilliformis. Its closest relative is a genuine conjugation system, the AvhB/TraG system of the cryptic plasmid pATC58 of Agrobacterium tumefaciens. The Bartonella VirB/VirD4 system is encoded by an operon of 10 genes (virB2-virB11). Seven Bartonella-translocated effector proteins (BepA-BepG) and the coupling protein VirD4 are encoded within 22 kb downstream of the virB operon. The entire virB/virD4/bep region probably constitutes a pathogenicity island. ... |
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| VirB type IV secretion system |
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Phagosome acidification is required for intracellular expression of the VirB type IV secretion system. The LuxR family regulator VjbR regulated the virB operon directly by bounding a fragment of the virB promoter containing an 18 bp palindromic motif. ... |
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| Type IV secretion system |
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C. jejuni pVir is a 37-kb plasmid harboring 54 predicted ORFs, contains genes for homologs of Com and Vir proteins, and shows great similarities to type IV secretion proteins found in cag PAI of H. pylori. ... |
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| Type IV secretion system |
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A pilus-like structure crossing the inner and outer membrane of the bacterium and like a needle inserts into the membrane of host cell. ... |
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Rvh T4SS
(Rickettsiales vir homolog (rvh) T4SS) |
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All sequenced Rickettsia genomes encode a P-T4SS similar to the vir archetype of Agrobacterium tumefaciens and related systems, and this T4SS is encoded across all genomes in the rickettsial families Rickettsiaceae, Anaplasmataceae, and Midichloriaceae. Lacks a homolog of VirB5, the minor pilin subunit that is indispensable for pilus formation but not substrate transfer. A defining feature of the rvh T4SS is the proliferation of genes encoding RvhB6 proteins, which are predicted IM channel components of the VirB6/TrbL family that are required for substrate transfer in P-T4SSs. Three other components are encoded by duplicate genes within the rvh T4SS: RvhB4a and RvhB4b--homologous to VirB4 (IM ATPase), RvhB9a and RvhB9b--homologous to Vir9 (participating with VirB7 and VirB10 in the OM pore of the T4SS), two VirB8-like channel proteins, RvhB8a and RvhB8b. ... |
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| Rvh T4SS |
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Similar to the virB/virD system of A. tumefaciens. The T4SS of Rickettsiales is characterized by an expansion of the virB4 and virB6 gene families and an absence of virB5. In addition, species in the family Anaplasmataceae have an expansion of virB2 and are missing virB1. The presence of multiple copies of T4SS components may facilitate environment- or host cell-dependent delivery of effector molecules. ... |
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| Rvh T4SS |
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Similar to the virB/virD system of A. tumefaciens. The T4SS of Rickettsiales is characterized by an expansion of the virB4 and virB6 gene families and an absence of virB5. In addition, species in the family Anaplasmataceae have an expansion of virB2 and are missing virB1. The presence of multiple copies of T4SS components may facilitate environment- or host cell-dependent delivery of effector molecules. ... |
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| Rvh T4SS |
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Similar to the virB/virD system of A. tumefaciens. The T4SS of Rickettsiales is characterized by an expansion of the virB4 and virB6 gene families and an absence of virB5. In addition, species in the family Anaplasmataceae have an expansion of virB2 and are missing virB1. The presence of multiple copies of T4SS components may facilitate environment- or host cell-dependent delivery of effector molecules. ... |
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