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InlF
(Internalin F) |
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An example of a virulence factor whose function may be only significant under specific host cell conditions or during infection of specific host species. ... |
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InlJ
(Internalin J) |
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PDB code: 3BZ5. A sortase anchored adhesin binds MUC2 (the major component of intestinal mucus) by its internalin domain. ... |
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InlP
(Internalin P) |
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Of the 25 known members of the L. monocytogenes internalin family, InlC and InlP are two of only four internalin family members that are thought to be secreted in a soluble form rather than anchored to the bacteria cell surface. ... |
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Lap
(Listeria adhesion protein) |
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Originally named surface protein p104, is a 104 kDa adhesion protein, present in every Listeria spp. except L. grayi. ... |
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| LapB |
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A sortase SrtA-anchored LPXTG protein. Necessary for adhesion to and entry into mammalian epithelial cell lines and for virulence in intravenous or orally infected mice. ... |
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| Antigen 85 |
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Three homologous proteins: antigen 85A, 85B and 85C, also known as fibronectin-binding protein (Fbp). ... |
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| HbhA |
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Surface-located protein. A multifunctional protein involved in adherence of Mycobacterium tuberculosis to non-phagocytic cells and in the formation of intracytosolic lipid inclusions. ... |
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| P97/P102 paralog family |
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Including P97 (mhp183), P102 (mhp182), P97 paralogs (mhp107, mhp493, mhp271, mhp385) and P102 paralogs (mhp683, mhp384). ... |
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| RTX protein |
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Many RTX proteins serve as major virulence factors of Gram-negative pathogens. These large, multidomain proteins share a common architecture comprised of four regions. First, C teminal end leading is the RTX export sequence that directs the protein through the T1SS. This is followed by the ligand-binding region responsible for host adhesion and cohesion, which contains diverse ligand-binding domains. Thereaftert is a large extension region consisting of tens to hundreds of tandem bacterial immunoglobulin-like domains. Lastly, there is a conserved N terminal cell-membrane-anchor region. ... |
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rOmpA/Sca0
(Surface cell antigen 0) |
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Conserved throughout the spotted fever group. Studies have suggested that rOmpA plays a role in adhesion, but recent studies indicate that rOmpA is not critical for virulence in a guinea pig model but may play a role in survival or transmission from the tick vector. ... |
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