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Compound category: Benzene and substituted derivatives
(total 172 related compounds in database, current show from 81 to 90)
 
Compound name 2D structure Target pathogen(s) Related VF/VFcategory Max phase Reference(s)
N'-[(E)-(2,4-dihydroxyphenyl)methylidene]-4-nitrobenzohydrazide Depiction based on curated SMILES _ O O + N O HO OH N N H Escherichia TTSS (Type III secretion system) Preclinical (in vitro) Tree JJ, et al. 2009. Infect Immun; Wang D, et al. 2011. J Biol Chem
N-[3-(2-amino-1H-imidazol-5-yl)phenyl]-4-pentylbenzamide;hydrochloride Depiction based on curated SMILES HN ClH H 2 N N H N H 3 C O Escherichia Biofilm Preclinical (in vitro) Bunders CA, et al. 2010. Bioorg Med Chem Lett
N-[4-(2-amino-1H-imidazol-5-yl)phenyl]-3,5-difluorobenzamide;hydrochloride Depiction based on curated SMILES N H ClH F F O H 2 N N H N Escherichia
Pseudomonas		 Biofilm
Biofilm		 Preclinical (in vitro)
Preclinical (in vitro)		 Bunders CA, et al. 2010. Bioorg Med Chem Lett
N-[4-(2-amino-1H-imidazol-5-yl)phenyl]-4-pentylbenzamide;hydrochloride Depiction based on curated SMILES N H ClH H 2 N N H N CH 3 O Escherichia Biofilm Preclinical (in vitro) Bunders CA, et al. 2010. Bioorg Med Chem Lett
N-[4-(2-amino-1H-imidazol-5-yl)phenyl]-3,5-dichlorobenzamide Depiction based on curated SMILES NH 2 Cl Cl O N H N H N Francisella Regulation Preclinical (in vitro) Milton ME, et al. 2017. Mol Microbiol
(4Z)-2-benzyl-4-[(3-bromo-4-methoxyphenyl)methylidene]-5-(trifluoromethyl)pyrazol-3-one Depiction based on curated SMILES Br F F F O H 3 C N N O Haemophilus LOS Preclinical (in vitro) Xu Y, et al. 2018. Bioorg Med Chem
1-Phenyl-3-(trifluoromethyl)-4-[(Z)-3-(benzyloxy)benzylidene]-2-pyrazoline-5-one Depiction based on curated SMILES F F F O N N O Haemophilus LOS Preclinical (in vitro) Xu Y, et al. 2018. Bioorg Med Chem
1-Phenyl-3-(trifluoromethyl)-4-[(Z)-3-bromo-4-methoxybenzylidene]-2-pyrazoline-5-one Depiction based on curated SMILES Br F F F O H 3 C N N O Haemophilus LOS Preclinical (in vitro) Xu Y, et al. 2018. Bioorg Med Chem
(4Z)-4-[(4-chlorophenyl)methylidene]-2-phenyl-5-(trifluoromethyl)pyrazol-3-one Depiction based on curated SMILES F F F N Cl O N Haemophilus LOS Preclinical (in vitro) Xu Y, et al. 2018. Bioorg Med Chem
3-[(4Z)-4-[(3-bromo-4-methoxyphenyl)methylidene]-5-oxo-3-(trifluoromethyl)pyrazol-1-yl]-N-(2-hydroxyethyl)benzamide Depiction based on curated SMILES Br F F F OH NH O CH 3 O N N O Haemophilus LOS Preclinical (in vitro) Xu Y, et al. 2018. Bioorg Med Chem
   


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