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Compound category: Benzene and substituted derivatives
(total 172 related compounds in database, current show from 71 to 80)
 
Compound name 2D structure Target pathogen(s) Related VF/VFcategory Max phase Reference(s)
Compound 4
(internal name in literature)		 Depiction based on curated SMILES NH O NH 2 O NH N Clostridium Exotoxin; Regulation Preclinical (in vitro) Thanissery R, et al. 2018. Front Microbiol
Compound 7
(internal name in literature)		 Depiction based on curated SMILES NH N HN NH 2 N O NH N Clostridium Exotoxin; Regulation Preclinical (in vitro) Thanissery R, et al. 2018. Front Microbiol
Compound 9
(internal name in literature)		 Depiction based on curated SMILES NH N Br HN NH 2 N O NH N Clostridium Exotoxin; Regulation Preclinical (in vitro) Thanissery R, et al. 2018. Front Microbiol
Compound 11
(internal name in literature)		 Depiction based on curated SMILES N HN NH 2 N CH 3 HN O N N H Clostridium Exotoxin; Regulation Preclinical (in vitro) Thanissery R, et al. 2018. Front Microbiol
2-hydroxy-5-[2-[4-(2-phenyl-1,3-thiazol-4-yl)phenyl]-1,3-thiazol-4-yl]benzamide Depiction based on curated SMILES S OH N N NH 2 S O Enterococcus
Staphylococcus		 Others; Adherence; Biofilm
Others; Adherence; Biofilm		 Preclinical (in vitro)
Preclinical (in vitro)		 Oniga SD, et al. 2017. Molecules
4-(4-chlorophenyl)-2-[4-(2-phenyl-1,3-thiazol-4-yl)phenyl]-1,3-thiazole Depiction based on curated SMILES N N S Cl S Enterococcus
Staphylococcus		 Others; Adherence; Biofilm
Others; Adherence; Biofilm		 Preclinical (in vitro)
Preclinical (in vitro)		 Oniga SD, et al. 2017. Molecules
4-[2-[4-(2-phenyl-1,3-thiazol-4-yl)phenyl]-1,3-thiazol-4-yl]benzonitrile Depiction based on curated SMILES N S N S N Enterococcus
Staphylococcus		 Others; Adherence; Biofilm
Others; Adherence; Biofilm		 Preclinical (in vitro)
Preclinical (in vitro)		 Oniga SD, et al. 2017. Molecules
2-[4-(2-Phenyl-4-thiazolyl)phenyl]-4-(4-nitrophenyl)thiazole Depiction based on curated SMILES _ O O + N S N S N Enterococcus
Staphylococcus		 Others; Adherence; Biofilm
Others; Adherence; Biofilm		 Preclinical (in vitro)
Preclinical (in vitro)		 Oniga SD, et al. 2017. Molecules
5-methyl-4-phenyl-2-[4-(2-phenyl-1,3-thiazol-4-yl)phenyl]-1,3-thiazole Depiction based on curated SMILES S N CH 3 S N Enterococcus
Staphylococcus		 Others; Adherence; Biofilm
Others; Adherence; Biofilm		 Preclinical (in vitro)
Preclinical (in vitro)		 Oniga SD, et al. 2017. Molecules
4-(5-Bromosalicylideneamino)-N-(2-thiazolyl)benzenesulfonamide Depiction based on curated SMILES OH Br N O S N HN O S Escherichia TTSS (Type III secretion system) Preclinical (in vitro) Gauthier A, et al. 2005. Antimicrob Agents Chemother
   


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