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Compound category: Organoheterocyclic compounds
(total 30 related compounds in database, current show from 11 to 20)
 
Compound name 2D structure Target pathogen(s) Related VF/VFcategory Max phase Reference(s)
(5R,6R)-5,6-bis[[4-(3-methylbutyl)triazol-1-yl]methyl]-4,5,6,7-tetrahydro-1H-benzimidazol-2-amine Depiction based on curated SMILES N N H 3 C CH 3 N N H H 2 N N N N CH 3 N H 3 C H H Acinetobacter
Pseudomonas		 Biofilm
Biofilm		 Preclinical (in vitro)
Preclinical (in vitro)		 Huigens RW 3rd, et al. 2009. Org Biomol Chem
(5R,6R)-5,6-bis[[4-(cyclohexylmethyl)triazol-1-yl]methyl]-4,5,6,7-tetrahydro-1H-benzimidazol-2-amine Depiction based on curated SMILES N H N N N N N H N H N H 2 N Acinetobacter Biofilm Preclinical (in vitro) Huigens RW 3rd, et al. 2009. Org Biomol Chem
(5R,6R)-5,6-bis[[4-(cyclopentylmethyl)triazol-1-yl]methyl]-4,5,6,7-tetrahydro-1H-benzimidazol-2-amine Depiction based on curated SMILES N H N N N N NH N N H NH 2 Acinetobacter
Pseudomonas		 Biofilm
Biofilm		 Preclinical (in vitro)
Preclinical (in vitro)		 Huigens RW 3rd, et al. 2009. Org Biomol Chem
(5R,6R)-5,6-bis[[4-(phenoxymethyl)triazol-1-yl]methyl]-4,5,6,7-tetrahydro-1H-benzimidazol-2-amine Depiction based on curated SMILES O N N H N N N N HN N H NH 2 O Acinetobacter
Pseudomonas		 Biofilm
Biofilm		 Preclinical (in vitro)
Preclinical (in vitro)		 Huigens RW 3rd, et al. 2009. Org Biomol Chem
1-(tert-butyl)-7-chloro-6-fluoro-1,4-dihydro-4-oxo-1,8-napthyridine-3-carboxylic acid Depiction based on curated SMILES N Cl F O CH 3 HO O N H 3 C H 3 C Acinetobacter Biofilm Preclinical (in vitro) Na SH, et al. 2021. J Microbiol
3-(furan-2-ylmethyl)-2-(((5-hydroxy-1H-pyrazol-3-yl)methyl)thio)-6,7-dihydro-3H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-4(5H)-one Depiction based on curated SMILES S O N O OH NH N S N Acinetobacter
Salmonella		 Biofilm
Biofilm		 Preclinical (in vitro)
Preclinical (in vitro)		 Koopman JA, et al. 2015. Antimicrob Agents Chemother
Gallein Depiction based on curated SMILES HO OH O HO HO O O Acinetobacter
Klebsiella		 Others; Biofilm
Others; Biofilm		 Preclinical (in vitro)
Preclinical (in vitro)		 Roberge N, et al. 2021. Front Microbiol
3,4,5-trimethoxy-N-(5,5,6,6-tetramethylbenzo[b][1]benzazepin-11-yl)benzamide Depiction based on curated SMILES N H O CH 3 O H 3 C O H 3 C O H 3 C CH 3 N CH 3 CH 3 Acinetobacter Biofilm Preclinical (in vitro) Sambanthamoorthy K, et al. 2015. Bioorg Med Chem Lett
3-(2-amino-1H-imidazol-5-yl)-N-tridecan-7-ylpropanamide;hydrochloride Depiction based on curated SMILES CH 3 ClH H 2 N N H N O N H CH 3 Acinetobacter
Pseudomonas		 Biofilm
Biofilm		 Preclinical (in vitro)
Preclinical (in vitro)		 Ballard TE, et al. 2008. Chemistry
Furanone Depiction based on curated SMILES O O Acinetobacter Biofilm Preclinical (in vitro) Peng Q, et al. 2020. Sci Rep
   


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