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Compound category: Benzenoids
(total 25 related compounds in database, current show from 21 to 25)
 
Compound name 2D structure Target pathogen(s) Related VF/VFcategory Max phase Reference(s)
N'-(3,5-dichloro-2-hydroxybenzylidene)benzohydrazide Depiction based on curated SMILES OH Cl O Cl N N H Escherichia
Salmonella
TTSS (Type III secretion system)
TTSS (SPI-1 encode); TTSS (SPI-2 encode)
Preclinical (in vitro)
Preclinical (in vitro)
Tree JJ, et al. 2009. Infect Immun; Wang D, et al. 2011. J Biol Chem
Negrea A, et al. 2007. Antimicrob Agents Chemother
N-[3-(2-amino-1H-imidazol-5-yl)phenyl]-4-pentylbenzamide;hydrochloride Depiction based on curated SMILES HN ClH H 2 N N H N H 3 C O Escherichia Biofilm Preclinical (in vitro) Bunders CA, et al. 2010. Bioorg Med Chem Lett
N-[4-(2-amino-1H-imidazol-5-yl)phenyl]-3,5-difluorobenzamide;hydrochloride Depiction based on curated SMILES N H ClH F F O H 2 N N H N Escherichia
Pseudomonas
Biofilm
Biofilm
Preclinical (in vitro)
Preclinical (in vitro)
Bunders CA, et al. 2010. Bioorg Med Chem Lett
N-[4-(2-amino-1H-imidazol-5-yl)phenyl]-4-pentylbenzamide;hydrochloride Depiction based on curated SMILES N H ClH H 2 N N H N CH 3 O Escherichia Biofilm Preclinical (in vitro) Bunders CA, et al. 2010. Bioorg Med Chem Lett
N-[[(E)-(3,5-dichloro-2-hydroxyphenyl)methylideneamino]carbamothioyl]-2,2-dimethylpropanamide Depiction based on curated SMILES N OH Cl Cl CH 3 NH S N H O H 3 C H 3 C Escherichia TTSS (Type III secretion system) Preclinical (in vitro) Gauthier A, et al. 2005. Antimicrob Agents Chemother
   
   
   
   
   
   
   
   
   
   
   


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