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VF category: T7SS effectors (total 38 related VFs in database, current show from 1 to 10)
 
VF Bacteria Brief description
CpnT
Mycobacterium
(M. tuberculosis H37Rv)
 Secreted by ESX-5. CpnT is a two-domain protein in which the toxic activity resides in the C-terminus. ...
ESAT-6/CFP-10
(Early secretory antigenic target of 6 kDa/culture filtrate protein of 10 kDa)
Mycobacterium
(M. tuberculosis H37Rv)
 Secreted protein. ESAT-6 and CFP-10 proteins are cotranscribed and form a tight 1:1 complex. A striking feature of the CFP-10/ESAT-6 complex is the long flexible arm formed by the C-terminus of CFP-10, which is essential for binding to the surface of cells. PDB code:1wa8. ...
EsxG-EsxH
Mycobacterium
(M. tuberculosis H37Rv)
 EsxG-EsxH heterodimer is secreted by ESX-3. EsxG-EsxH heterodimer of M. tuberculosis can inhibit host endosomal sorting complex required for transport (ESCRT) machinery, raising the possibility that M. tuberculosis impairs this host response. EsxG-EsxH also facilitated secretion of several members of the proline-glutamic acid (PE) and proline-proline-glutamic acid (PPE) protein families that play roles in iron acquisition. ...
ESAT-6/CFP-10
(Early secretory antigenic target of 6 kDa/culture filtrate protein of 10 kDa)
Mycobacterium
(M. canettii CIPT 140070008)
 Secreted protein. ESAT-6 and CFP-10 proteins are cotranscribed and form a tight 1:1 complex. A striking feature of the CFP-10/ESAT-6 complex is the long flexible arm formed by the C-terminus of CFP-10, which is essential for binding to the surface of cells. PDB code:1wa8. ...
ESAT-6/CFP-10
(Early secretory antigenic target of 6 kDa/culture filtrate protein of 10 kDa)
Mycobacterium
(M. canettii CIPT 140070010)
 Secreted protein. ESAT-6 and CFP-10 proteins are cotranscribed and form a tight 1:1 complex. A striking feature of the CFP-10/ESAT-6 complex is the long flexible arm formed by the C-terminus of CFP-10, which is essential for binding to the surface of cells. PDB code:1wa8. ...
ESAT-6/CFP-10
(Early secretory antigenic target of 6 kDa/culture filtrate protein of 10 kDa)
Mycobacterium
(M. canettii CIPT 140070017)
 Secreted protein. ESAT-6 and CFP-10 proteins are cotranscribed and form a tight 1:1 complex. A striking feature of the CFP-10/ESAT-6 complex is the long flexible arm formed by the C-terminus of CFP-10, which is essential for binding to the surface of cells. PDB code:1wa8. ...
ESAT-6/CFP-10
(Early secretory antigenic target of 6 kDa/culture filtrate protein of 10 kDa)
Mycobacterium
(M. gilvum PYR-GCK)
 Secreted protein. ESAT-6 and CFP-10 proteins are cotranscribed and form a tight 1:1 complex. A striking feature of the CFP-10/ESAT-6 complex is the long flexible arm formed by the C-terminus of CFP-10, which is essential for binding to the surface of cells. PDB code:1wa8. ...
ESAT-6/CFP-10
(Early secretory antigenic target of 6 kDa/culture filtrate protein of 10 kDa)
Mycobacterium
(M. gilvum Spyr1)
 Secreted protein. ESAT-6 and CFP-10 proteins are cotranscribed and form a tight 1:1 complex. A striking feature of the CFP-10/ESAT-6 complex is the long flexible arm formed by the C-terminus of CFP-10, which is essential for binding to the surface of cells. PDB code:1wa8. ...
ESAT-6/CFP-10
(Early secretory antigenic target of 6 kDa/culture filtrate protein of 10 kDa)
Mycobacterium
(M. leprae Br4923)
 Secreted protein. ESAT-6 and CFP-10 proteins are cotranscribed and form a tight 1:1 complex. A striking feature of the CFP-10/ESAT-6 complex is the long flexible arm formed by the C-terminus of CFP-10, which is essential for binding to the surface of cells. PDB code:1wa8. ...
ESAT-6/CFP-10
(Early secretory antigenic target of 6 kDa/culture filtrate protein of 10 kDa)
Mycobacterium
(M. leprae TN)
 Secreted protein. ESAT-6 and CFP-10 proteins are cotranscribed and form a tight 1:1 complex. A striking feature of the CFP-10/ESAT-6 complex is the long flexible arm formed by the C-terminus of CFP-10, which is essential for binding to the surface of cells. PDB code:1wa8. ...
   


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