GspA
(global stress gene)
Keywords: Stress protein;
Functions: 19-kDa GroEL-like
Dispensable for bacterial survival and growth in macrophage infection
References: Abu Kwaik Y, et al., 1997. Transcriptional regulation of the macrophage-induced gene (gspA) of Legionella pneumophila and phenotypic characterization of a null mutant. Mol. Microbiol. 24(3):629-642.
KatAB
Related genes: katA;
katB;
Keywords: Stress protein;
Functions: A periplasmic catalase, expressed maximally during the postexponential phase
Important for intracellular survival and transmission
References: Bandyopadhyay P, Steinman HM, 1998. Legionella pneumophila catalase-peroxidases: cloning of the katB gene and studies of KatB function. J. Bacteriol. 180(20):5369-5374.
Bandyopadhyay P, Steinman HM, 2000. Catalase-peroxidases of Legionella pneumophila: cloning of the katA gene and studies of KatA function. J. Bacteriol. 182(23):6679-6686.
Bandyopadhyay P, et al., 2003. Legionella pneumophila catalase-peroxidases are required for proper trafficking and growth in primary macrophages. Infect. Immun. 71(8):4526-4535.
SodB
Related genes: sodB;
Keywords: Stress protein;
Functions: A cytoplasmic iron superoxide dismutase
Important for intracellular survival and transmission
References: Sadosky AB, et al., 1994. The iron superoxide dismutase of Legionella pneumophila is essential for viability. J. Bacteriol. 176(12):3790-3799.
SodC
Related genes: sodC;
Keywords: Stress protein;
Functions: A periplasmic copper-zinc superoxide dismutase
Important for intracellular survival and transmission
References: St John G, Steinman HM, 1996. Periplasmic copper-zinc superoxide dismutase of Legionella pneumophila: role in stationary-phase survival. J. Bacteriol. 178(6):1578-1584.
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