LPS
Keywords: Endotoxin; Phase variation;
Structure features:
O-side chain is made up of homopolymer repeats of a single sugar residue designated legionaminic acid, and the core region is highly O-acetylated providing hydrophobic characteristic on the LPS structure
Functions:
Phase variation associated with changes in virulence
References:
Luneberg E, et al., 1998. Phase-variable expression of lipopolysaccharide contributes to the virulence of Legionella pneumophila. J. Exp. Med. 188(1):49-60.
Luneberg E, et al., 2001. Chromosomal insertion and excision of a 30 kb unstable genetic element is responsible for phase variation of lipopolysaccharide and other virulence determinants in Legionella pneumophila. Mol. Microbiol. 39(5):1259-1271.

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