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Pathogenicity islands in Shigella : SHI-2


SHI-2 (Shigella)


View the legend tRNA-Sec intC shiA shiB tnpA tnpB IS3 SF3703 IS3 shiC SF3705 SF3706 IS629 SF3705 yi22 yi21_g2 SF3710 shiD tnpH SF3713 shiF iucA iucB iucC iucD iucD iutA SF3720 yi22 yi21_g2

Full Name: Shigella pathogenicity island 2
Species: flexneri (serotype 2a)
Strain: 301
Replicon: chromosome
Accession: AE005674 (NC_004337)
Location: 3806404~3831722 bp
Size: 24 Kbp
G+C content (%): 48.6/51 (PAI/Genome)
Inserted locus:
selC tRNA gene
A sequence homologous to the integrase gene of CP4 bacteriophages lies adjacent to selC
Phenotype:
Harbours genes involved in aerobactin-mediated iron acquisition, colicin V immunity and cryptic IS elements.
The aerobactin genes have characteristics of transmissible elements. They are found on plasmids, including pColV and F1me in certain strains of E. coli and Salmonella, respectively.
Remark:
SHI-2 is present in the same location in Shigella sonnei, but the aerobactin genes are not located within SHI-2 in Shigella boydii or enteroinvasive E. coli. Shigella dysenteriae.
Reference:
Moss JE, et al., 1999. The selC-associated SHI-2 pathogenicity island of Shigella flexneri. Mol Microbiol 33(1):74-83.
Vokes SA, et al., 1999. The aerobactin iron transport system genes in Shigella flexneri are present within a pathogenicity island. Mol. Microbiol. 33(1):63-73.








SHI-1 (also called <i>she</i>) Back to Top SHI-3
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