Full Name: Shigella pathogenicity island 2
Species: flexneri (serotype 2a)
Location: 3806404~3831722 bp
Size: 24 Kbp
G+C content (%): 48.6/51 (PAI/Genome)
selC tRNA gene
A sequence homologous to the integrase gene of CP4 bacteriophages lies adjacent to selC
Harbours genes involved in aerobactin-mediated iron acquisition, colicin V immunity and cryptic IS elements.
The aerobactin genes have characteristics of transmissible elements. They are found on plasmids, including pColV and F1me in certain strains of E. coli and Salmonella, respectively.
SHI-2 is present in the same location in Shigella sonnei, but the aerobactin genes are not located within SHI-2 in Shigella boydii or enteroinvasive E. coli. Shigella dysenteriae.
Moss JE, et al., 1999. The selC-associated SHI-2 pathogenicity island of Shigella flexneri. Mol Microbiol 33(1):74-83.
Vokes SA, et al., 1999. The aerobactin iron transport system genes in Shigella flexneri are present within a pathogenicity island. Mol. Microbiol. 33(1):63-73.
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