VFDB - comparative pathogenomic composition of Legionella

Comparison of pathogenomic composition of Legionella. Total 4 genomes available.

Virulence factors	Related genes	L. pneumophila Philadelphia 1	L. pneumophila Paris	L. pneumophila Lens	L. pneumophila Corby
Virulence factors	Related genes	chromosome NC_002942	chromosome NC_006368	chromosome NC_006369	chromosome NC_009494
Adherence
Hsp60	htpB	lpg0688	lpp0743	lpl0724	LPC_2606
MOMP	omp28	lpg1974	lpp1958	lpl1952	LPC_1461
Type IV pili	pilB	lpg1522	lpp1479	lpl1504	LPC_0941
	pilC	lpg1523	lpp1480	lpl1503	LPC_0942
	pilD	lpg1524	lpp1481	lpl1502	LPC_0943
	pilE	lpg1914	lpp1889	lpl1878	LPC_1368
	pilE	lpg1915	lpp1890	lpl1879	LPC_1369
	pilQ	lpg0931	lpp0993	lpl0962	LPC_2359
	pilP	lpg0930	lpp0992	lpl0961	LPC_2360
	pilO	lpg0929	lpp0991	lpl0960	LPC_2361
	pilN	lpg0928	lpp0990	lpl0959	LPC_2362
	pilM	lpg0927	lpp0989	lpl0958	LPC_2363
Intracellular survival
LigA	ligA	lpg0693	lpp0748	lpl0730	LPC_2601
LvgA	lvgA	lpg0525	lpp0590	lpl0571	LPC_2777
Mip	mip	lpg0791	lpp0855	lpl0829	LPC_2500
Invasion
Enhanced entry proteins	enhA	lpg2641	lpp2694	lpl2566	LPC_0498
	-	lpg1336	lpp1290	lpl1289	LPC_0752
	-	lpg1386	lpp1341	lpl1337	LPC_0802
	-	lpg0910	lpp0972	lpl0942	LPC_2381
	-	lpg0704	lpp0759	lpl0741	LPC_2590
	enhB	lpg2640	lpp2693	lpl2565	LPC_0500
	enhC	lpg2639	lpp2692	lpl2564	LPC_0501
	lidL	lpg1172	lpp1174	lpl1180	LPC_0638
	-	lpg1356	lpp1310	lpl1307	LPC_0770
	-	lpg1350	lpp2174	lpl1303	LPC_0766
	-	lpg1062		lpl1059	LPC_2212
Iron acquisition
Cytochrome c muturation (ccm) locus	ccmA	lpg0856	lpp0918	lpl0887	LPC_2439
	ccmB	lpg0857	lpp0919	lpl0888	LPC_2438
	ccmC	lpg0858	lpp0920	lpl0889	LPC_2437
	ccmD	lpg0859	lpp0921	lpl0890	LPC_2436
	ccmE	lpg0860	lpp0922	lpl0891	LPC_2435
	ccmF	lpg0861	lpp0923	lpl0892	LPC_2433
Ferrous iron transport	feoB	lpg2657	lpp2711	lpl2584	LPC_0482
Ferrous iron transport	feoA	lpg2658	lpp2712	lpl2585	LPC_0481
Fur-regulated gene	frgA	lpg2800	lpp2846	lpl2715	LPC_3086
Iron acquisition/assimilation locus	iraA	lpg0747	lpp0813	lpl0784	LPC_2545
Iron acquisition/assimilation locus	iraB	lpg0746	lpp0812	lpl0783	LPC_2546
Legiobactin	lbtA	lpg1325	lpp1280	lpl1279	LPC_0740
Legiobactin	lbtB	lpg1324	lpp1279	lpl1278	LPC_0739
Regulation
Alternative sigma factor RpoS	rpoS	lpg1284	lpp1247	lpl1247	LPC_0709
Carbon storage regulator A	csrA	lpg0781	lpp0845	lpl0820	LPC_2513
LetA/LetS two component	letA	lpg2646	lpp2699	lpl2571	LPC_0493
LetA/LetS two component	letS	lpg1912	lpp1887	lpl1876	LPC_1366
RelA	relA	lpg1457	lpp1413	lpl1571	LPC_0872
Secretion system
Dot/Icm type IVB secretion system	icmT	lpg0441	lpp0507	lpl0483	LPC_2902
	icmS	lpg0442	lpp0508	lpl0484	LPC_2901
	icmR	lpg0443	lpp0509	lpl0485	LPC_2900
	icmQ	lpg0444	lpp0510	lpl0486	LPC_2899
	icmP/dotM	lpg0445	lpp0511	lpl0487	LPC_2898
	icmO/dotL	lpg0446	lpp0512	lpl0488	LPC_2897
	icmN/dotK	lpg0447	lpp0513	lpl0489	LPC_2896
	icmM/dotJ	lpg0448	lpp0514	lpl0490	LPC_2895
	icmL/dotI	lpg0449	lpp0515	lpl0491	LPC_2894
	icmK/dotH	lpg0450	lpp0516	lpl0492	LPC_2893
	icmE/dotG	lpg0451	lpp0517	lpl0493	LPC_2892
	icmG/dotF	lpg0452	lpp0518	lpl0494	LPC_2891
	icmC/dotE	lpg0453	lpp0519	lpl0495	LPC_2890
	icmD/dotP	lpg0454	lpp0520	lpl0496	LPC_2889
	icmJ/dotN	lpg0455	lpp0521	lpl0497	LPC_2888
	icmB/dotO	lpg0456	lpp0522	lpl0498	LPC_2887
	icmF	lpg0458	lpp0524	lpl0500	LPC_2885
	icmH/dotU	lpg0459	lpp0525	lpl0501	LPC_2884
	dotD	lpg2674	lpp2728	lpl2601	LPC_0463
	dotC	lpg2675	lpp2729	lpl2602	LPC_0462
	dotB	lpg2676	lpp2730	lpl2603	LPC_0461
	dotA	lpg2686	lpp2740	lpl2613	LPC_0450
	icmV	lpg2687	lpp2741	lpl2614	LPC_0449
	icmW	lpg2688	lpp2742	lpl2615	LPC_0448
	icmX	lpg2689	lpp2743	lpl2616	LPC_0447
Lsp type II secretion system	lspD	lpg1320	lpp1275	lpl1274	LPC_0735
	lspE	lpg1319	lpp1274	lpl1273	LPC_0734
	lspF	lpg1363	lpp1317	lpl1314	LPC_0779
	lspG	lpg1362	lpp1316	lpl1313	LPC_0778
	lspH	lpg1361	lpp1315	lpl1312	LPC_0777
	lspI	lpg1360	lpp1314	lpl1311	LPC_0776
	lspJ	lpg1359	lpp1313	lpl1310	LPC_0775
	lspK	lpg1358	lpp1312	lpl1309	LPC_0774
	lspL	lpg1874	lpp1839	lpl1836	LPC_1319
	lspM	lpg1875	lpp1840	lpl1837	LPC_1320
	lspC	lpg0895	lpp0956	lpl0926	LPC_2398
Lvh (Legionella vir homologs) type IVA secretion system	lvhB2		lpp0169	lpl0151
	lvhB3	lpg1255	lpp0170	lpl0152
	lvhB4	lpg1254	lpp0171	lpl0153
	lvhB5	lpg1253	lpp0172	lpl0154
	lvhB7	lpg1252	lpp0173	lpl0155
	lvhB6	lpg1250	lpp0175	lpl0157
	lvhB8	lpg1249	lpp0176	lpl0158
	lvhB9	lpg1248	lpp0177	lpl0159
	lvhB10	lpg1247	lpp0178	lpl0160
	lvhB11	lpg1246	lpp0179	lpl0161
	lvhD4	lpg1245	lpp0180	lpl0162
Type IVB secretion effectors	ralF	lpg1950	lpp1932	lpl1919	LPC_1423
	lidA	lpg0940	lpp1002	lpl0971	LPC_2349
	lepA	lpg2793	lpp2839	lpl2708	LPC_3079
	lepB	lpg2490	lpp2555	lpl2411	LPC_1987
	wipA	lpg2718	lpp2775	lpl2646	LPC_0415
	wipB	lpg0642	lpp0696*	lpl0679	LPC_2651
	wipC	lpg2206	lpp2157	lpl2131	LPC_1671
	ylfA	lpg2298	lpp2246	lpl2217	LPC_1763
	ylfB	lpg1884	lpp1848	lpl1845	LPC_1331
	sidA	lpg0621	lpp0675	lpl0658	LPC_2673
	sidB	lpg1642	lpp1612a*	lpl1384	LPC_1071
	sdbA	lpg0275	lpp0349	lpl0327	LPC_0352
	sdbB	lpg2482	lpp2546	lpl2402	LPC_1996
	sdbB-like		lpp0059	lpl0058	LPC_0065
	sdbC	lpg2391	lpp2458	lpl2315	LPC_2086
	sidC	lpg2511	lpp2579	lpl2433	LPC_1959
	sdcA	lpg2510	lpp2578	lpl2432	LPC_1960
	sdcB		lpp0209	lpl0189	LPC_0225
	sidD	lpg2465		lpl2385
	sidE/laiD	lpg0234	lpp0304	lpl0288	LPC_0309
	sdeA/laiA	lpg2157	lpp2096	lpl2085	LPC_1618
	sdeB/laiB	lpg2156	lpp2095	lpl2084	LPC_1605
	sdeC/laiC	lpg2153	lpp2092	lpl2081	LPC_1602
	sdeD/laiF	lpg2509	lpp2577	lpl2431	LPC_1961
	laiE	lpg2154	lpp2093	lpl2082	LPC_1603
	sidE-like		lpp2062	lpl2052	LPC_1570
	sidF	lpg2584	lpp2637	lpl2507	LPC_0561
	sidG	lpg1355	lpp1309
	sidH	lpg2829	lpp2883*
	sdhA	lpg0376	lpp0443	lpl0419	LPC_2967
	sdhB	lpg0135	lpp0150	lpl0135	LPC_0156
	vipA	lpg0390	lpp0457*	lpl0433	LPC_2954
	vipD1	lpg2831	lpp2888
	vipD2	lpg2410	lpp2479	lpl2334	LPC_2065
	vipD3	lpg1227	lpp1235	lpl1235	LPC_0696
	vipE	lpg2813	lpp2865	lpl2728
	vipF	lpg0103	lpp0117	lpl0103	LPC_0122
	drrA/sidM	lpg2464		lpl2384
Toxin
RtxA	rtxA	lpg2515	lpp2583	lpl2437	LPC_1955

Last update: Fri Nov 16 19:46:08 2007