Comparison of pathogenomic composition of Helicobacter. Total 8 genomes available.
 Virulence factors   # of related genes   H. acinonychis str. Sheeba   H. hepaticus ATCC 51449   H. pylori 26695   H. pylori G27   H. pylori HPAG1   H. pylori J99   H. pylori P12   H. pylori Shi470 
Acid resistance
 Urease    + + + ± + + + +
Adherence
 adherence-associated lipoprotein AlpA (hopC)    + - + + + + + +
 AlpB (hopB)    + - + + + + + +
 Blood group antigen binding adhesins    - - + + + + + +
 H. pylori adhesin A    + - + + + + + +
 HopZ    - - + + + + + -
 HorB    + - + + + + + +
 PEB1    - + - - - - - -
 Sialic acid binding adhesins    - - + + + + ± -
Immune evasion
 Lipopolysaccharide Lewis antigens    ± ± ± ± + + + ±
Immune modulator
 Neutrophil-activating protein (HP-NAP)    + + + + + + + +
 Outer inflammatory protein    - - + + + + + +
Motility
 Flagella   38  + ± + + + + + ±
Secretion system
 Cag PAI type IV secretion system   26  - - ± ± ± + + ±
 T4SS effectors cytotoxin-associated gene A    - - + + + + + +
Toxin
 Cytolethal distending toxin    - + - - - - - -
 Vacuolating cytotoxin    - - + + + + + +
Others
 DupA (duodenal ulcer promoting)    - - - - - - - +
 Plasticity region    - - - - - + + -
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Last update: Wed Dec 19 14:54:04 2018