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| Hyaluronidase |
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An important pathogenic bacterial spreading factor, and cleave hyaluronan, which is a constituent of the extracellular matrix of connective tissues. May also pave the way for deleterious effects of other bacterial toxins, thus increasing the magnitude of the damage. Another role may be to supply nutrients for the bacteria, since the degradation products of its target substrates are disaccharides that can be transported and metabolized intracellularly by bacteria. ... |
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| Hyaluronate lyase |
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Degradation of hyaluronic acid, contribute to local dissolution of the extracellular matrix. Cleaves the 1,4-glycosidic linkage between N-acetyl-b-D-glucosamine and D-glucuronic acid residues in hyaluronan and catalyzes the release of unsaturated polysaccharides, with the disaccharide unit 2-acetamido-2-deoxy-3- O-(β-D-gluco-4-enepyranosyluronic acid)-D-glucose being the main end product. ... |
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| Hyaluronidase |
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GAS are capable of producing two types of hyaluronidase, a bacteriophage associated enzyme and an extracellular hyaluronidase that is secreted from the cell. Since the capsule of GAS is composed solely of hyaluronic acid, the hyaluronidase presumably benefits the phage by aiding in capsule penetration during its infection of or release from streptococci. ... |
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| Hyaluronidase |
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PDB code: 1F1S. Facilitates spread of bacteria by breaking down the hyalurone polymers present in the extracellular matrices of the host. The GBS hyaluronate lyase also has limited specificity for achondroitin sulphate and cleaves the chain at unsulphated sites. This action may facilitate deep tissue penetration during infection. ... |
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| Hyaluronidase |
|
An important pathogenic bacterial spreading factor, and cleave hyaluronan, which is a constituent of the extracellular matrix of connective tissues. May also pave the way for deleterious effects of other bacterial toxins, thus increasing the magnitude of the damage. Another role may be to supply nutrients for the bacteria, since the degradation products of its target substrates are disaccharides that can be transported and metabolized intracellularly by bacteria. ... |
|
| Hyaluronidase |
|
An important pathogenic bacterial spreading factor, and cleave hyaluronan, which is a constituent of the extracellular matrix of connective tissues. May also pave the way for deleterious effects of other bacterial toxins, thus increasing the magnitude of the damage. Another role may be to supply nutrients for the bacteria, since the degradation products of its target substrates are disaccharides that can be transported and metabolized intracellularly by bacteria. ... |
|
| Hyaluronate lyase |
|
Degradation of hyaluronic acid, contribute to local dissolution of the extracellular matrix. Cleaves the 1,4-glycosidic linkage between N-acetyl-b-D-glucosamine and D-glucuronic acid residues in hyaluronan and catalyzes the release of unsaturated polysaccharides, with the disaccharide unit 2-acetamido-2-deoxy-3- O-(β-D-gluco-4-enepyranosyluronic acid)-D-glucose being the main end product. ... |
|
| Hyaluronate lyase |
|
Degradation of hyaluronic acid, contribute to local dissolution of the extracellular matrix. Cleaves the 1,4-glycosidic linkage between N-acetyl-b-D-glucosamine and D-glucuronic acid residues in hyaluronan and catalyzes the release of unsaturated polysaccharides, with the disaccharide unit 2-acetamido-2-deoxy-3- O-(β-D-gluco-4-enepyranosyluronic acid)-D-glucose being the main end product. ... |
|
| Hyaluronate lyase |
|
Degradation of hyaluronic acid, contribute to local dissolution of the extracellular matrix. Cleaves the 1,4-glycosidic linkage between N-acetyl-b-D-glucosamine and D-glucuronic acid residues in hyaluronan and catalyzes the release of unsaturated polysaccharides, with the disaccharide unit 2-acetamido-2-deoxy-3- O-(β-D-gluco-4-enepyranosyluronic acid)-D-glucose being the main end product. ... |
|
| Hyaluronate lyase |
|
Degradation of hyaluronic acid, contribute to local dissolution of the extracellular matrix. Cleaves the 1,4-glycosidic linkage between N-acetyl-b-D-glucosamine and D-glucuronic acid residues in hyaluronan and catalyzes the release of unsaturated polysaccharides, with the disaccharide unit 2-acetamido-2-deoxy-3- O-(β-D-gluco-4-enepyranosyluronic acid)-D-glucose being the main end product. ... |
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