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VF category: Type IV secretion system (T4SS) (total 163 related VFs in database, current show from 1 to 10)
 
VF Bacteria Brief description
Rvh T4SS secreted effectors
Anaplasma
(A. phagocytophilum HZ)
 T4SS effectors. ...
VirB/VirD4 T4SS secreted effectors
Bartonella
(B. henselae str. Houston-1)
 bepA (Bartonella effector protein BepA). bepB (Bartonella effector protein BepB). bepC (Bartonella effector protein BepC). ...
T4SS secreted effectors
Brucella
(B. melitensis bv. 1 str. 16M)
 BPE005 (type IV secretion system effector, cyclic nucleotide-binding domain-containing protein). ...
T4SS secreted effectors
Coxiella
(C. burnetii RSA 493)
 T4SS effectors. ...
Dot/Icm T4SS secreted effectors
Legionella
(L. pneumophila subsp. pneumophila str. Philadelphia 1)
 Type IVB secretion effectors. Adherence. ...
Rvh T4SS secreted effectors
Rickettsia
(R. typhi str. Wilmington)
 Rvh T4SS effector. ...
Rvh T4SS
Anaplasma
(A. phagocytophilum HZ)
 Similar to the virB/virD system of A. tumefaciens. The T4SS of Rickettsiales is characterized by an expansion of the virB4 and virB6 gene families and an absence of virB5. In addition, species in the family Anaplasmataceae have an expansion of virB2 and are missing virB1. The presence of multiple copies of T4SS components may facilitate environment- or host cell-dependent delivery of effector molecules. ...
Trw type IV secretion system
Bartonella
(B. henselae str. Houston-1)
 The Trw system of Bartonella, probably acquired from horizontal gene transfer, shares an extensive homology with the Trw system of the Trw conjugation machinery of the broad-host-range antibiotic-resistance plasmid R388. The trw genes of Bartonella are collinear with the respective genes of plasmid R388, except for the presence of multiple tandem gene duplications of trwL and trwJIH in Bartonella. The trwL (the homologue of the pilin virB2) and trwJ (the homologues of the minor pilus-associated component virB5) sequences are highly variable within the same Bartonella species, as well as between different species. But the various copies of trwH and trwI are almost identical. A remarkable difference between Trw systems of plasmid R388 and of Bartonella is the lack of the T4CP-encoding trwB gene in Bartonella. ...
VirB/VirD4 type IV secretion system
Bartonella
(B. henselae str. Houston-1)
 The VirB/VirD4 T4SS is well conserved within the genus Bartonella, although it is absent in B. bacilliformis. Its closest relative is a genuine conjugation system, the AvhB/TraG system of the cryptic plasmid pATC58 of Agrobacterium tumefaciens. The Bartonella VirB/VirD4 system is encoded by an operon of 10 genes (virB2-virB11). Seven Bartonella-translocated effector proteins (BepA-BepG) and the coupling protein VirD4 are encoded within 22 kb downstream of the virB operon. The entire virB/virD4/bep region probably constitutes a pathogenicity island. ...
VirB type IV secretion system
Brucella
(B. melitensis bv. 1 str. 16M)
 Phagosome acidification is required for intracellular expression of the VirB type IV secretion system. The LuxR family regulator VjbR regulated the virB operon directly by bounding a fragment of the virB promoter containing an 18 bp palindromic motif. ...
   


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