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VF category: Type IV pili (total 172 related VFs in database, current show from 1 to 10)
 
VF Bacteria Brief description
TFP
(Type IV pili)
Acinetobacter
(A. baumannii ACICU)
Essential for twitching motility and natural competence, and contribute to host cell adherence. ...
Flp type IV pili
Aeromonas
(A. hydrophila ML09-119)
Peritrichous. Resembles the Actinobacillus actinomycetemcomitans Flp pilus. Contributes to biofilm formation and autoagglutination. ...
MSHA type IV pili
(Mannose-sensitive haemagglutinin type IV pili)
Aeromonas
(A. hydrophila ML09-119)
Homology to the mannose-sensitive hemagglutinin pilus of Vibrio cholerae. MSHA bundle-forming pilus is the major filamentous appendage responsible for tissue adherence and colonisation. Essential for biofilm formation. ...
Tap type IV pili
Aeromonas
(A. hydrophila ML09-119)
Polar. Similar to the P. aeruginosa Pil system. Constitutively expressed. The role of the Tap pilus remains to be elucidated, its biogenesis has strong implications in virulence in other ways. TapD, a prepilin peptidase is not only required for the processing of the prepilins before they are incorporated into the pilus filament but also for the processing of the pseudopilins of the T2SS, that are essential for the secretion of many virulence factors. ...
Type IV pili
Burkholderia
(B. pseudomallei K96243)
Type IVa pili. Plays a role in adherence. ...
BFP
(Bundle-forming Pili)
Escherichia
(E. coli O127:H6 str. E2348/69)
The bfp gene cluster is encoded on EAF(EPEC adherence factor)plasmid. EAF plasmid also contains the per locus (plasmid-encoded regulator), the products of which regulate the bfp operon and most of the genes in the LEE by the LEE-encoded regulator (Ler). ...
Type IV pili
Francisella
(F. tularensis subsp. tularensis SCHU S4)
The genomes of the different F. tularensis subspecies. tularensis (type A), holarctica (type B), and novicida, all encode Tfp clusters including six putative pilin genes. ...
Type IV pili
Legionella
(L. pneumophila subsp. pneumophila str. Philadelphia 1)
Also designated as CAP (competence and adherence-associated pili). Contribute to complement-independent binding, perhaps as the ligand for protozoan lectin. ...
Type IV pili
Neisseria
(N. meningitidis MC58)
One or two different loci are used for the expression of the major pilin encoding gene (pilE), whereas various silent genes (pilS) are spread throughout the chromosome. Recombination between pilS and pilE copies leads to changes in the pilin coding sequence and subsequently to the expression of antigenically different pili. Mutations affecting the length of the homopolymeric G-run located in the region encoding the SP of PilC results in on/off changes in piliation. ...
Type IV pili
Pseudomonas
(P. aeruginosa PAO1)
pilA, B, C, D, E, F, M, N, O, P, Q, T, U, V, W, X, Y1, Y2, Z, and fimT, U, V are involved in the biogenesis and mechanical function of pili, pilG, H, I, K, chpA, B, C, D, E, pilS, R, fimS, rpoN, algR, algU, and vfr are involved in transcriptional regulation and chemosensory pathways that control the expression or activity of the twitching motility of the pili. ...
   


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